Binge Eating Disorder (BED)

Definition | Aetiology | Pathophysiology | Risk factors | Signs and symptoms | Investigations | Management

Definition

Binge Eating Disorder (BED) is a mental health condition characterised by recurrent episodes of excessive food consumption within a short period, accompanied by a sense of loss of control, without compensatory behaviours such as purging or excessive exercise.

Aetiology

  • Genetic factors: familial predisposition to eating disorders.
  • Neurobiological factors: dysregulation of dopamine and serotonin pathways.
  • Psychosocial factors: history of dieting, low self-esteem, or emotional distress.
  • Environmental influences: exposure to weight stigma or societal pressure regarding body image.

Pathophysiology

  • Impaired satiety regulation due to altered serotonin activity.
  • Increased reward-seeking behaviour associated with dopamine dysfunction.
  • Hypothalamic-pituitary-adrenal (HPA) axis dysregulation affecting stress response and appetite control.

Risk factors

  • Family history of eating disorders or obesity.
  • History of restrictive dieting or weight cycling.
  • Psychiatric comorbidities (e.g., depression, anxiety, substance misuse).
  • Emotional distress or trauma.
  • Childhood obesity or early exposure to disordered eating behaviours.

Signs and symptoms

  • Recurrent episodes of binge eating, often secretive.
  • Loss of control over eating during binge episodes.
  • Eating large quantities of food rapidly, even when not hungry.
  • Marked distress regarding binge eating behaviours.
  • Feelings of guilt, shame, or disgust after eating.
  • Physical consequences such as weight gain, metabolic syndrome, and gastrointestinal discomfort.

Investigations

  • Clinical assessment: comprehensive eating history, including triggers and emotional associations with eating.
  • Screening tools: Binge Eating Scale (BES), Eating Disorder Examination Questionnaire (EDE-Q).
  • Blood tests: FBC, U&Es, LFTs, lipid profile, HbA1c to assess metabolic impact.
  • Body mass index (BMI): to evaluate weight-related health risks.

Management

1. Psychological therapies:

  • Cognitive Behavioural Therapy for Eating Disorders (CBT-E) as first-line treatment.
  • Interpersonal therapy (IPT) to address emotional triggers.
  • Mindfulness-based interventions to improve awareness and reduce impulsive eating.

2. Pharmacological management:

  • First-line: Selective serotonin reuptake inhibitors (SSRIs) (e.g., fluoxetine) to reduce binge episodes.
  • Second-line: Lisdexamfetamine or topiramate for severe or treatment-resistant cases.

3. Lifestyle modifications:

  • Regular meal patterns to reduce binge triggers.
  • Physical activity to improve mood and overall well-being.
  • Addressing emotional eating with structured coping strategies.

4. Referral:

  • Eating disorder services: for structured therapeutic intervention.
  • Dietitian: for nutritional counselling and weight management.
  • Psychiatrist: for pharmacological treatment in severe cases.